GEMIFLOXACIN MESYLATE

Stock Code: 3575179
Manufacturer Part No: SML1625-5MG
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Biochem/physiol Actions


Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.


Packaging


5, 25 mg in glass bottle

Colourwhite to light brown
Quality Level100
InChI keyJIYMVSQRGZEYAX-CWUUNJJBSA-N
InChI1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27)
ManufacturerSIGMA-ALDRICH
SolubilityH2O: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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