A01 (Smurf 1 Inhibitor)

A01 (Smurf 1 Inhibitor)

Biochem/physiol Actions

A01 is a high affinity selective inhibitor of E3 ubiquitin-protein ligase Smurf1 (Smad ubiquitination regulatory factor-1) that disturbs Smurf1-Smad1/5 interaction and blocks Smurf1 mediated Smad1/5 ubiquitination. A01 increases responsiveness to BMP-2 in myoblasts and osteoblasts.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574867 A01 (Smurf 1 Inhibitor) white to beige 100 QFYLTUDRXBNZFQ-UHFFFAOYSA-N 1S/C22H20ClF3N4O3S/c1-15-8-9-27-30(15)17-4-2-16(3-5-17)21(31)28-10-12-29(13-11-28)34(32,33)18-6-7-20(23)19(14-18)22(24,25)26/h2-9,14H,10-13H2,1H3 SIGMA-ALDRICH 2-8°C DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£401.14 (exc VAT) per 25MG
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3574868 A01 (Smurf 1 Inhibitor) white to beige 100 QFYLTUDRXBNZFQ-UHFFFAOYSA-N 1S/C22H20ClF3N4O3S/c1-15-8-9-27-30(15)17-4-2-16(3-5-17)21(31)28-10-12-29(13-11-28)34(32,33)18-6-7-20(23)19(14-18)22(24,25)26/h2-9,14H,10-13H2,1H3 SIGMA-ALDRICH 2-8°C DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
£132.88 (exc VAT) per 5MG
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