TREPROSTINIL

TREPROSTINIL

Biochem/physiol Actions

Treprostinil is a stable synthetic analog of prostacyclin (prostaglandin PGI2), an IP receptor agonist used clinically for the treatment of pulmonary arterial hypertension. It is a potent vasodilator with antithrombotic, antiproliferative and anti-inflammatory properties.

Treprostinil elicits a longer half-life when compared with iloprost. It mediates inhibition of transforming growth factor-? (TGF-?) and nuclear factor-?B (NF-?B) signaling pathways. Treprostinil effectively reduces right ventricular systolic pressure and inhibits the recruitment of circulating fibrocyte.

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price
3575040 TREPROSTINIL white to beige 100 IQKAWAUTOKVMLE-DQHZMXPSSA-M 1S/C23H34O5.Na/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25;/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27);/q;+1/p- SIGMA-ALDRICH powder ≥98% (HPLC)
You need to be logged in to see prices.
3575041 TREPROSTINIL white to beige 100 IQKAWAUTOKVMLE-DQHZMXPSSA-M 1S/C23H34O5.Na/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25;/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27);/q;+1/p- SIGMA-ALDRICH powder ≥98% (HPLC)
You need to be logged in to see prices.
You need to be logged in to see prices.