MARINOPYRROLE A

MARINOPYRROLE A

Biochem/physiol Actions

Marinopyrrole A (Maritoclax) is a potent and selective inhibitor of Bcl-2 family member Mcl-1, originally isolated from marine streptomycetes for its antimicrobial activity against methicillin-resistant Staphylococcus aureus. Marinopyrrole A directly binds to Mcl-1 and targets it for proteasomal degradation. Marinopyrrole A induced apoptosis in Mcl-1-dependent cancer cells and sensitized cancer cells to ABT-737.

General description

Marinopyrrole A (Maritoclax) is a member of phenolic 1,3?-bipyrroles family targeting actin group.

Packaging

5, 25 mg in glass bottle

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price
3575044 MARINOPYRROLE A light yellow to dark yellow 100 SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥95% (HPLC)
You need to be logged in to see prices.
3575045 MARINOPYRROLE A light yellow to dark yellow 100 SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥95% (HPLC)
You need to be logged in to see prices.
You need to be logged in to see prices.