EC23

EC23

Biochem/physiol Actions

EC23 is a synthetic, photostable all-trans retinoic acid (ATRA) analog/mimetic that targets RAR with greater affinity than ATRA (RARα/β/γ EC50 by cell-free TR-FRET binding assay = 3.7/3.3/16.8 with EC23 vs. 16.0/17.6/14.7 nM with ATRA) and does not bind retinoid x receptors (RXRs). EC23 induces differentiation of human pluripotent embryonic stem cells (0.1-10 µM) with a similar or better efficiency than ATRA.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576269 EC23 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
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3576270 EC23 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
Click Add to Quote for price and delivery
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