UVI3003

UVI3003

Biochem/physiol Actions

UVI3003 is a high-affinity selective Pan-retinoid X receptor (RXR) full antagonist. Retinoid actions are predominantly mediated through the formation of various RAR and RXR isotype heterodimers that can act as either transcriptional repressors or activators. UVI3003 has been used as a tool to test the contribution of RXR to transactivation by a given RXR heterodimer. It was found to induce teratogenesis in zebrafish embryos and recently was found to inhibit A?42 aggregation.

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575604 UVI3003 white to beige 100 SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£391.39 (exc VAT) per 25MG
-
+
3575605 UVI3003 white to beige 100 SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£121.32 (exc VAT) per 5MG
-
+