ADDA 5 HYDROCHLORIDE

Application

ADDA 5 hydrochloride has been used as a complex IV inhibitor to study its effects on leptomeningeal derivatives of human breast and lung cancer cells.

Biochem/physiol Actions

ADDA 5 is a potent and selective inhibitor of cytochrome c oxidase (Complex IV) that depletes the bioenergetics reserve capacity in intact glioma cells. ADDA 5 specifically inhibits the proliferation of chemosensitive and chemoresistant glioma cells, while sparing non-cancer cells. Additionally ADDA 5 is effective against glioma stem cells.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575587 ADDA 5 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£391.39 (exc VAT) per 25MG
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3575588 ADDA 5 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
£121.32 (exc VAT) per 5MG
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