Carboxyamidotriazole, >=98% (HPLC)

Carboxyamidotriazole, >=98% (HPLC)

Biochem/physiol Actions

Carboxyamidotriazole (CAI) is a non-cytotoxic anticancer drug. It exhibits anti-inflammatory properties and reduces the release of proinflammatory cytokines. CAI prevents the proliferation and invasive behavior of a variety of human cancer cell types and endothelial cells in vitro and in vivo. It is used to treat several acute and chronic inflammation models, like adjuvant arthritis and inflammatory bowel diseases (IBD). CAI blocks tumor cell proliferation and stimulates cell apoptosis in vitro.

Carboxyamidotriazole (L-651582) is an orally active calcium channel blocker. Carboxyamidotriazole blocks intracellular and mitochondrial calcium entry and flux, resulting in inhibition of cell proliferation, calcium-release-activated calcium channel (CRAC) function, and maintenance of mitochondrial membrane potential.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574063 Carboxyamidotriazole, >=98% (HPLC) white to beige 100 WNRZHQBJSXRYJK-UHFFFAOYSA-N 1S/C17H12Cl3N5O2/c18-10-3-1-9(2-4-10)15(26)13-11(19)5-8(6-12(13)20)7-25-16(21)14(17(22)27)23-24-25/h1-6H,7,21H2,(H2,22,27) SIGMA-ALDRICH DMSO: 10 mg/mL (clear solution) powder ≥98% (HPLC)
£423.43 (exc VAT) per 25MG
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3574064 Carboxyamidotriazole, >=98% (HPLC) white to beige 100 WNRZHQBJSXRYJK-UHFFFAOYSA-N 1S/C17H12Cl3N5O2/c18-10-3-1-9(2-4-10)15(26)13-11(19)5-8(6-12(13)20)7-25-16(21)14(17(22)27)23-24-25/h1-6H,7,21H2,(H2,22,27) SIGMA-ALDRICH DMSO: 10 mg/mL (clear solution) powder ≥98% (HPLC)
£154.61 (exc VAT) per 5MG
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