THPN

THPN

Biochem/physiol Actions

THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model.

General description

THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B.

Other Notes

air sensitive

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3575067 THPN white to beige 100 NVFRHTFJDGAFQS-UHFFFAOYSA-N 1S/C15H22O4/c1-2-3-4-5-6-7-8-12(16)11-9-13(17)15(19)14(18)10-11/h9-10,17-19H,2-8H2,1H3 SIGMA-ALDRICH DMSO: 25 mg/mL, clear powder ≥98% (HPLC)
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3575068 THPN white to beige 100 NVFRHTFJDGAFQS-UHFFFAOYSA-N 1S/C15H22O4/c1-2-3-4-5-6-7-8-12(16)11-9-13(17)15(19)14(18)10-11/h9-10,17-19H,2-8H2,1H3 SIGMA-ALDRICH DMSO: 25 mg/mL, clear powder ≥98% (HPLC)
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