LCAT ACTIVATOR COMPOUND A

LCAT ACTIVATOR COMPOUND A

Biochem/physiol Actions

LCAT activator compound A is an activator of Lecithin:cholesterol acyltransferase (LCAT) including some mutant LCATs found in Familial LCAT Deficiency (FLD). LCAT activator compound A forms a covalent hydrophobic adduct with LCAT Cys 31. The chronic treatment with LCAT activator compound A results in a significant increase in HDLc, HDL particle, size, plasma apolipoprotein A-I level, plasma cholesteryl ester to free cholesterol ratio, and a significant reduction in very low-density lipoprotein cholesterol in hamsters.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575753 LCAT ACTIVATOR COMPOUND A white to brown SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
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3575754 LCAT ACTIVATOR COMPOUND A white to brown SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
Click Add to Quote for price and delivery
-
+