TAZAROTENIC ACID

TAZAROTENIC ACID

Biochem/physiol Actions

Tazarotene is transformed to tazarotenic acid with the help of esterases. Tazarotenic acid regulates the pathogenic aspects of psoriasis through normalizing abnormal keratinocyte differentiation. It possesses strong anti-hyperproliferative effects in skin and reduces inflammation.

Tazarotenic acid, an active metabolite of tazarotene, is a potent and selective agonist of the retinoid receptor (RAR) that binds to RARα, RARβ, and RARγ. Tazarotenic acid relatively selective activates RARβ and RARγ. Tazarotenic acid is a first xenobiotic substrate of human retinoic acid hydroxylase CYP26A1 and CYP26B1.

Packaging

5, 25 mg in glass bottle

No detailed specifications are available for this product.

There are no downloads for this product.

Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price
3575169 TAZAROTENIC ACID white to light brown 100 IQIBKLWBVJPOQO-UHFFFAOYSA-N 1S/C19H17NO2S/c1-19(2)9-10-23-17-8-4-13(11-16(17)19)3-6-15-7-5-14(12-20-15)18(21)22/h4-5,7-8,11-12H,9-10H2,1-2H3,(H,21,22) SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
You need to be logged in to see prices.
3575170 TAZAROTENIC ACID white to light brown 100 IQIBKLWBVJPOQO-UHFFFAOYSA-N 1S/C19H17NO2S/c1-19(2)9-10-23-17-8-4-13(11-16(17)19)3-6-15-7-5-14(12-20-15)18(21)22/h4-5,7-8,11-12H,9-10H2,1-2H3,(H,21,22) SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
You need to be logged in to see prices.
You need to be logged in to see prices.