ZM323881 HYDROCHLORIDE

ZM323881 HYDROCHLORIDE

Biochem/physiol Actions

ZM323881 is also known as (5?{[7?(benzyloxy) quinazolin?4?yl]amino}?4?fluoro?2?methylphenol). It is capable of blocking the efflux function and altering breast cancer resistant protein (BCRP)-related multidrug resistance (MDR).

ZM323881 is a selective inhibitor of VEGFR-2 with an IC50 value of 2 nM. ZM323881 is selective for VEGFR-2 over VEGFR-1 and other receptor tyrosine kinases including PDGFRβ, FGFR1, EGFR and erbB2. ZM323881 inhibited VEGF-A-induced endothelial cell proliferation with an IC50 value of 8 nM.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575274 ZM323881 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C DMSO: 10 mg/mL, clear powder ≥98% (HPLC)
£508.39 (exc VAT) per 25MG
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3575275 ZM323881 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C DMSO: 10 mg/mL, clear powder ≥98% (HPLC)
£156.00 (exc VAT) per 5MG
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