TIPELUKAST

TIPELUKAST

Biochem/physiol Actions

Tipelukast is a Leukotriene D4 (LTD4) receptor antagonist and an inhibitor of 5-lipoxygenase (5-LO) and also phosphodiesterases PDE3 and PDE4. It has been found to have antifibrotic and anti-inflammatory activity. Tipelukast has been investigated as a possible treatment for nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).

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Code Description Colour InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3576214 TIPELUKAST white to beige KPWYNAGOBXLMSE-UHFFFAOYSA-N 1S/C29H38O7S/c1-5-9-23-25(14-12-22(20(4)31)29(23)36-16-7-11-27(32)33)35-17-8-18-37-26-15-13-21(19(3)30)28(34)24(26)10-6-2/h12-15,34H,5-11,16-18H2,1-4H3,(H,32,3 SIGMA-ALDRICH DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
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3576215 TIPELUKAST white to beige KPWYNAGOBXLMSE-UHFFFAOYSA-N 1S/C29H38O7S/c1-5-9-23-25(14-12-22(20(4)31)29(23)36-16-7-11-27(32)33)35-17-8-18-37-26-15-13-21(19(3)30)28(34)24(26)10-6-2/h12-15,34H,5-11,16-18H2,1-4H3,(H,32,3 SIGMA-ALDRICH DMSO: 2 mg/mL, clear powder ≥98% (HPLC)
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