PHIKAN083 HYDROCHLORIDE

Biochem/physiol Actions

PhiKan083 is a small molecule that binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3575361 PHIKAN083 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C H2O: 2 mg/mL, clear powder ≥98% (HPLC)
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3575362 PHIKAN083 HYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C H2O: 2 mg/mL, clear powder ≥98% (HPLC)
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