UCN-01, >=97% (HPLC), powder

UCN-01, >=97% (HPLC), powder

Application

UCN-01 has been used to study checkpoint kinase-1 (CHK1) protein function in trophoblast stem (TS) cells. It has also been used to study UV-induced CHK1 phosphorylation in IB10 cells.

Biochem/physiol Actions

UCN-01 is a selective inhibitor for conventional PKC isotypes over novel PKC isotypes.

Features and Benefits

This compound is featured on the PKB/Akt and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

1, 5 mg in glass bottle

Preparation Note

UCN-01 is soluble in DMSO at a concentration that is greater than 5 mg/ml. However, it is insoluble in water.

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Code Description Colour Quality Level Manufacturer Solubility Form Assay Price
3576988 UCN-01, >=97% (HPLC), powder light yellow 100 SIGMA-ALDRICH DMSO: >5 mg/mL, H2O: insoluble powder ≥97% (HPLC)
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3576989 UCN-01, >=97% (HPLC), powder light yellow 100 SIGMA-ALDRICH DMSO: >5 mg/mL, H2O: insoluble powder ≥97% (HPLC)
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