SERTACONAZOLE NITRATE

SERTACONAZOLE NITRATE

Biochem/physiol Actions

Sertaconazole nitrate is an antifungal agent with anti-inflammatory and anti-itch activity. Topical administration of this drug reduces the releases of cytokines from activated T-cell enriched human lymphocytes. Sertaconazole nitrate has been used as a highly safe and effective therapeutic for treating tinea pedis interdigitalis. It is also used to treat contact hypersensitivity and irritant contact dermatitis.

Sertaconazole nitrate is an imidazole antifungal. Like other imidazole antifungals, sertaconazole blocks the synthesis of ergosterol, an essential component of the fungal cell membrane, by inhibiting the P450 enzyme 14α-demethylase that converts lanosterol to ergosterol.

Packaging

10, 50 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574206 SERTACONAZOLE NITRATE white to beige 100 HAAITRDZHUANGT-UHFFFAOYSA-N 1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4) SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£52.93 (exc VAT) per 10MG
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3574207 SERTACONAZOLE NITRATE white to beige 100 HAAITRDZHUANGT-UHFFFAOYSA-N 1S/C20H15Cl3N2OS.HNO3/c21-14-4-5-16(18(23)8-14)19(9-25-7-6-24-12-25)26-10-13-11-27-20-15(13)2-1-3-17(20)22;2-1(3)4/h1-8,11-12,19H,9-10H2;(H,2,3,4) SIGMA-ALDRICH −20°C DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
£206.14 (exc VAT) per 50MG
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