INDY

INDY

Biochem/physiol Actions

INDY is a potent inhibitor of Dyrk1A and Dyrk1B (dual-specificity tyrosine-phosphorylation-regulated kinase 1). The IC50 values for inhibition of Dyrk1A and 1B are 240 and 230 nM, respectively. INDY impairs the self-renewal capacity of neural stem cells and glioblastoma tumor-initiating cells.

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574355 INDY white to beige 100 SIGMA-ALDRICH −20°C DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
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3574356 INDY white to beige 100 SIGMA-ALDRICH −20°C DMSO: 5 mg/mL, clear (warmed) powder ≥98% (HPLC)
Click Add to Quote for price and delivery
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