SOBETIROME

SOBETIROME

Biochem/physiol Actions

Sobetirome is also termed as 2-(4-(4-(benzyloxy)-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid/ GC-1. It has an inner-ring and negatively charged carboxylate groups at physiological pH. Sobetirome is considered as a cholesterol lowering agent in humans.

Sobetirome is an orally active and potent agonist at thyroid hormone receptor (TR) β and TRα that displays selective tissue action. Sobetirome is devoid of thyrotoxic adverse effects on the heart, bone, and skeletal muscle.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price
3575522 SOBETIROME white to beige 100 QNAZTOHXCZPOSA-UHFFFAOYSA-N 1S/C20H24O4/c1-12(2)17-9-15(5-6-19(17)21)10-18-13(3)7-16(8-14(18)4)24-11-20(22)23/h5-9,12,21H,10-11H2,1-4H3,(H,22,23) SIGMA-ALDRICH −20°C DMSO: 10 mg/mL, clear powder ≥98% (HPLC)
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3575523 SOBETIROME white to beige 100 QNAZTOHXCZPOSA-UHFFFAOYSA-N 1S/C20H24O4/c1-12(2)17-9-15(5-6-19(17)21)10-18-13(3)7-16(8-14(18)4)24-11-20(22)23/h5-9,12,21H,10-11H2,1-4H3,(H,22,23) SIGMA-ALDRICH −20°C DMSO: 10 mg/mL, clear powder ≥98% (HPLC)
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