RHYNCHOPHYLLINE

RHYNCHOPHYLLINE

Biochem/physiol Actions

Rhynchophylline is a spirocyclic alkaloid isolated from Uncaria species that exibits numerous pharmacological activities including hypotensive, neuroprotective, anticonvulsive, antiepileptic, antiarrhythmic, anticoagulant, antispasmodic, and sedative. Rhynchophylline modulates voltage-gated K+ (Kv) channel slow inactivation in mouse neuroblastoma N2A cells. Also it acts as noncompetitive antagonists of NMDA receptor channels in Xenopus oocytes.

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Code Description Colour InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3576175 RHYNCHOPHYLLINE white to beige DAXYUDFNWXHGBE-KAXDATADSA-N 1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-, SIGMA-ALDRICH DMSO: 2 mg/mL, clear (warmed) powder ≥95% (HPLC)
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3576176 RHYNCHOPHYLLINE white to beige DAXYUDFNWXHGBE-KAXDATADSA-N 1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-, SIGMA-ALDRICH DMSO: 2 mg/mL, clear (warmed) powder ≥95% (HPLC)
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