RS-127445 hydrochloride, >=98% (HPLC), powder

RS-127445 hydrochloride, >=98% (HPLC), powder

Biochem/physiol Actions

RS-127445 is a selective; high affinity; orally bioavailable serotonin 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi=9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price
3573877 RS-127445 hydrochloride, >=98% (HPLC), powder white to tan 100 MKJPYBJBPRFMHL-UHFFFAOYSA-N 1S/C17H16FN3.ClH/c1-10(2)15-9-16(21-17(19)20-15)13-7-8-14(18)12-6-4-3-5-11(12)13;/h3-10H,1-2H3,(H2,19,20,21);1H SIGMA-ALDRICH powder ≥98% (HPLC)
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3573878 RS-127445 hydrochloride, >=98% (HPLC), powder white to tan 100 MKJPYBJBPRFMHL-UHFFFAOYSA-N 1S/C17H16FN3.ClH/c1-10(2)15-9-16(21-17(19)20-15)13-7-8-14(18)12-6-4-3-5-11(12)13;/h3-10H,1-2H3,(H2,19,20,21);1H SIGMA-ALDRICH powder ≥98% (HPLC)
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