OGERIN NEGATIVE CONTROL

OGERIN NEGATIVE CONTROL

Biochem/physiol Actions

Ogerin negative control is a structurally similar analog of ogerin (catalog no. SML1482). Ogerin is a selective positive allosteric modulator of an orphan GPCR, GPR68, also known as Ovarian cancer G-protein coupled receptor 1 (OGR1). GPR68 is one of the proton or pH-sensing GPCRs that sense extracellular H(+). Ogerin potently potentiated proton-mediated GPR68-Gs signaling. The meta-analog is inactive and serves as a negative control.

Packaging

5, 25 mg in glass bottle

Recommended products

The positive allosteric modulator, ogerin, is available from Sigma. To learn more about and purchase ogerin, click here.

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price
3574970 OGERIN NEGATIVE CONTROL white to beige 100 RVKAHYFWSKSSQQ-UHFFFAOYSA-N 1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22) SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
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3574971 OGERIN NEGATIVE CONTROL white to beige 100 RVKAHYFWSKSSQQ-UHFFFAOYSA-N 1S/C17H17N5O/c18-16-20-15(14-8-4-7-13(9-14)11-23)21-17(22-16)19-10-12-5-2-1-3-6-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22) SIGMA-ALDRICH DMSO: 20 mg/mL, clear powder ≥98% (HPLC)
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