Alantolactone, >=98% (HPLC)

Alantolactone, >=98% (HPLC)

Application

Alantolactone has been used:in cell viability assayto examine the percentage of multicentrosomal mitosis in low and high passage human embryonic stem cells (hESC)in assessment of degranulation

Biochem/physiol Actions

Alantolactone is a sesquiterpene lactone disrupts the Cripto-1/ActRII complexes, resulting in an induction of activin/SMAD3 signaling. Alantolactone inhibits proliferation in cancer cells with no affect on normal cells.

General description

Alantolactone is a compound produced by Inula helenium. Alantolactone has antibacterial, antifungal, anti-inflammatory and anticancer properties. It suppresses signal transducer and activator of transcription 3 (STAT3) activation in liver and breast cancer cells. Alantolactone induces apoptosis in A549 lung cancer cells.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price
3574070 Alantolactone, >=98% (HPLC) white to beige 100 PXOYOCNNSUAQNS-AGNJHWRGSA-N 1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1 SIGMA-ALDRICH DMSO: 15 mg/mL (clear solution) powder ≥98% (HPLC)
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3574071 Alantolactone, >=98% (HPLC) white to beige 100 PXOYOCNNSUAQNS-AGNJHWRGSA-N 1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1 SIGMA-ALDRICH DMSO: 15 mg/mL (clear solution) powder ≥98% (HPLC)
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