SAPACITABINE

SAPACITABINE

Biochem/physiol Actions

Sapacitabine is an orally active prodrug of nucleoside analog CNDAC that exhibits potent anti-tumor activity in both blood and solid tumors. CNDAC incorporates into DNA where it causes single-strand breaks (SSBs), which are converted into double strand breaks (DSBs) during S phase.

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Code Description Colour InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3576549 SAPACITABINE white to beige LBGFKUUHOPIEMA-PEARBKPGSA-N 1S/C26H42N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-23(32)28-22-16-17-30(26(34)29-22)25-20(18-27)24(33)21(19-31)35-25/h16-17,20-21,24-25,31,33H,2-15,19H2,1H3,(H SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear powder ≥95% (HPLC)
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3576550 SAPACITABINE white to beige LBGFKUUHOPIEMA-PEARBKPGSA-N 1S/C26H42N4O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-23(32)28-22-16-17-30(26(34)29-22)25-20(18-27)24(33)21(19-31)35-25/h16-17,20-21,24-25,31,33H,2-15,19H2,1H3,(H SIGMA-ALDRICH −20°C DMSO: 2 mg/mL, clear powder ≥95% (HPLC)
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