SB 699551 DIHYDROCHLORIDE

SB 699551 DIHYDROCHLORIDE

Application

SB 699551 dihydrochloride has been used to identify the antagonism of 5-HT2AR in cell culture-derived hepatitis C virus (HCVcc).

Biochem/physiol Actions

SB 699551 dihydrochloride is also known as (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4?-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride). It is considered as a useful tool to explain the physiological roles of the 5-ht5A receptor.

SB-699551 is a 5-HT5A receptor antagonist, (pKi = 8.3) with 100-fold selectivity over other 5-HT receptor populations. SB-699551 completely blocks 5-HT-induced [35S]GTPγS membrane binding in cells expressing recombinant guinea pig 5-HT-5A.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3574169 SB 699551 DIHYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C H2O: 1 mg/mL, clear (warmed) powder ≥98% (HPLC)
£429.00 (exc VAT) per 25MG
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3574170 SB 699551 DIHYDROCHLORIDE white to beige 100 SIGMA-ALDRICH 2-8°C H2O: 1 mg/mL, clear (warmed) powder ≥98% (HPLC)
£133.30 (exc VAT) per 5MG
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