PRAMLINTIDE ACETATE

PRAMLINTIDE ACETATE

Biochem/physiol Actions

Pramlintide (AC0137, AC137, triPro-amylin) is a synthetic antidiabetic peptide that corresponds to human amylin (aa34-70) with proline substitutions at N25, S28 and S29 to limit the self-aggregation seen with native amylin. Pramlintide augments endogenous amylin-mediated glycemic control (blood glucose regulation) in vivo by delaying gastric emptying and inhibiting the secretion of glucagon, a catabolic hormone that opposes the effects of insulin and amylin.

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Code Description Colour Manufacturer Storage Temp. Form Assay Price
3576435 PRAMLINTIDE ACETATE white to off-white SIGMA-ALDRICH −20°C powder ≥95% (HPLC)
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3576436 PRAMLINTIDE ACETATE white to off-white SIGMA-ALDRICH −20°C powder ≥95% (HPLC)
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