LIXIVAPTAN

LIXIVAPTAN

Biochem/physiol Actions

Arginine vasopressin (AVP) plays an important part in circulatory and water homoeostasis and is important in renal hemodynamic alterations, water retention, and cardiac remodeling in congestive heart failure (CHF). Lixivaptan is an AVP V2-receptor selective antagonist that increases water excretion and normalizes serum sodium levels. Lixivaptan has been in clinical trials for hyponatremia associated with heart failure.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Further Info Solubility Form Assay Price Quantity
3574101 LIXIVAPTAN white to beige 100 PPHTXRNHTVLQED-UHFFFAOYSA-N 1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33) SIGMA-ALDRICH 4% w/w in ethyl acetate DMSO: 20 mg/mL, clear powder ≥96% (HPLC)
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3574102 LIXIVAPTAN white to beige 100 PPHTXRNHTVLQED-UHFFFAOYSA-N 1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33) SIGMA-ALDRICH 4% w/w in ethyl acetate DMSO: 20 mg/mL, clear powder ≥96% (HPLC)
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