SPA70

Biochem/physiol Actions

SPA70 is a cell penetrant, potent and highly selective human pregnane X receptor (hPXR) antagonist that inhibits hPXR in humanized mouse models. It inhibits hPXR-mediated drug metabolism in in primary human hepatocytes and in mouse models.

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Code Description Colour Manufacturer Storage Temp. Solubility Form Assay Price
3576654 SPA70 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear (warmed) powder ≥98% (HPLC)
3576655 SPA70 white to beige SIGMA-ALDRICH 2-8°C DMSO: 2 mg/mL, clear (warmed) powder ≥98% (HPLC)
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