6-THIO-2-DEOXYGUANOSINE

6-THIO-2-DEOXYGUANOSINE

Application

6-Thio-2?-Deoxyguanosine has been used in secreted luciferase enzyme activity in tonsillar cancer cells.

Biochem/physiol Actions

6-Thio-2′-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that is incorporated into de novo–synthesized telomeres. 6-Thio-2′-deoxyguanosine induces telomere dysfunction and rapid cell death in cancer cells, while spearing telomerase-negative cells.

Packaging

5, 25 mg in glass bottle

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Code Description Colour Quality Level InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3574715 6-THIO-2-DEOXYGUANOSINE white to brown 100 SCVJRXQHFJXZFZ-HSUXUTPPSA-N 1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5-,6-/m1/s1 SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥97% (HPLC)
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3574716 6-THIO-2-DEOXYGUANOSINE white to brown 100 SCVJRXQHFJXZFZ-HSUXUTPPSA-N 1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5-,6-/m1/s1 SIGMA-ALDRICH DMSO: 5 mg/mL, clear (warmed) powder ≥97% (HPLC)
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