R-568 HYDROCHLORIDE

R-568 HYDROCHLORIDE

Biochem/physiol Actions

R-568 is a positive allosteric modulator of the calcium-sensing receptor (CaSR), increasing the sensitivity to activation by extracellular Ca2+. In rats, orally administered R-568 decreases plasma levels of PTH and Ca2+ and, at higher doses, increases plasma levels of calcitonin.

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Code Description Colour InChI key InChI Manufacturer Solubility Form Assay Price Quantity
3575896 R-568 HYDROCHLORIDE white to beige YJXUXANREVNZLH-PFEQFJNWSA-N 1S/C18H22ClNO.ClH/c1-14(16-8-5-10-17(13-16)21-2)20-12-6-9-15-7-3-4-11-18(15)19;/h3-5,7-8,10-11,13-14,20H,6,9,12H2,1-2H3;1H/t14-;/m1./s1 SIGMA-ALDRICH DMSO: 2 mg/mL, clear (warmed) powder ≥95% (HPLC)
£490.29 (exc VAT) per 25MG
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3575897 R-568 HYDROCHLORIDE white to beige YJXUXANREVNZLH-PFEQFJNWSA-N 1S/C18H22ClNO.ClH/c1-14(16-8-5-10-17(13-16)21-2)20-12-6-9-15-7-3-4-11-18(15)19;/h3-5,7-8,10-11,13-14,20H,6,9,12H2,1-2H3;1H/t14-;/m1./s1 SIGMA-ALDRICH DMSO: 2 mg/mL, clear (warmed) powder ≥95% (HPLC)
£121.32 (exc VAT) per 5MG
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