SB 204741, , >98% (HPLC)

SB 204741, , >98% (HPLC)

Application

SB 204741 has been used as a 5-hydroxytryptamine receptor 2B (Htr2B) antagonist: to inhibit Htr2b signaling to test its effect on hepatic stellate cell (HSC) activation in three-month-old adult zebrafishto test its effect on the inhibition of fluoxetine effects in depressive-like behavioral studies in miceto test its effect in reducing scratching behavior evoked by sertraline in mice

Biochem/physiol Actions

5-HT2B serotonin receptor antagonist.

SB 204741 reduces the synaptic facilitation induced by the low dose of buprenorphine in spinal C-fiber synapses.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Packaging

10, 50 mg in glass bottle

No detailed specifications are available for this product.

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Code Description Colour Quality Level InChI key InChI Manufacturer Form Assay Price
3573888 SB 204741, , >98% (HPLC) off-white to tan 100 USFUFHFQWXDVMH-UHFFFAOYSA-N 1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19) SIGMA-ALDRICH solid >98% (HPLC)
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3573889 SB 204741, , >98% (HPLC) off-white to tan 100 USFUFHFQWXDVMH-UHFFFAOYSA-N 1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19) SIGMA-ALDRICH solid >98% (HPLC)
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