DIAPOCYNIN

DIAPOCYNIN

Stock Code: 3574254
Manufacturer Part No: SML0927-25MG
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£413.68 (exc VAT) per 25MG
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Biochem/physiol Actions


Diapocynin, a proposed NADPH oxidase (NOX) inhibitor, is an anti-inflammatory and antioxidant agent. Diapocynin attenuates oxidative damage and neuroinflammatory responses in animal model of Parkinson’;s disease. Diapocynin reverses deficient motor coordination in LRRK2R1441Gtg mice of PD.


Diapocynin is a covalent dimer of apocynin, and a functional metabolite of the same. It is generated by neutrophil activation via myeloperoxidase-mediated oxidation. Studies show that diapocynin has greater neuroprotection compared to apocynin.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
SolubilityDMSO: 2 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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