ZOSUQUIDAR HYDROCHLORIDE >=98% (HPLC)
Biochem/physiol Actions
Zosuqidar is a potent inhibitor of P-glycoprotein (P-gp, MDR1) a transporter protein that is a key modulator of cellular drug efflux. Zosuquidar sensitizes AML, and other cancer cell lines to cytotoxic drugs.
Features and Benefits
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Packaging
5 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| InChI key | VQJFFWJUYDGTQZ-FCNWNIDBSA-N |
| InChI | 1S/C32H31F2N3O2.ClH/c33-32(34)29-22-7-1-3-9-24(22)31(25-10-4-2-8-23(25)30(29)32)37-17-15-36(16-18-37)19-21(38)20-39-28-13-5-12-27-26(28)11-6-14-35-27;/h1-14,21 |
| Manufacturer | SIGMA-ALDRICH |
| Solubility | H2O: 4 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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