ZM323881 HYDROCHLORIDE

ZM323881 HYDROCHLORIDE

Stock Code: 3575274
Manufacturer Part No: SML1691-25MG
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£508.39 (exc VAT) per 25MG
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Biochem/physiol Actions


ZM323881 is also known as (5?{[7?(benzyloxy) quinazolin?4?yl]amino}?4?fluoro?2?methylphenol). It is capable of blocking the efflux function and altering breast cancer resistant protein (BCRP)-related multidrug resistance (MDR).


ZM323881 is a selective inhibitor of VEGFR-2 with an IC50 value of 2 nM. ZM323881 is selective for VEGFR-2 over VEGFR-1 and other receptor tyrosine kinases including PDGFRβ, FGFR1, EGFR and erbB2. ZM323881 inhibited VEGF-A-induced endothelial cell proliferation with an IC50 value of 8 nM.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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