URB597, >=98% (HPLC), powder

Stock Code: 3576986
Manufacturer Part No: U4133-25MG
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Biochem/physiol Actions


Potent, selective fatty acid amide hydrolase (FAAH) inhibitor.


General description


URB597 binds to active sites of fatty acid amide hydrolases and inhibits their activity. URB597 alters expression of tyrosine hydroxylase and interacts with abnormal-cannabidiol (Abn-CBD) and peroxisome proliferator-activated receptors (PPARs). URB597 elicits antinociception property via cannabinoid receptor by maintaining endocannabinoid anandamide (AEA) levels. URB597 reduces abnormal hyperactivity in neurons and could be for treatment of seizures and improving synaptic plasticity.


Packaging


5, 25 mg in glass bottle


Preparation Note


URB597 is soluble in DMSO at a concentration that is approximately 14 mg/ml.

Colourwhite
Quality Level100
InChI keyROFVXGGUISEHAM-UHFFFAOYSA-N
InChI1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: soluble ~14 mg/mL
Formpowder
Assay≥98% (HPLC)

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