ULIPRISTAL ACETATE

Stock Code: 3574954
Manufacturer Part No: SML1469-10MG
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Biochem/physiol Actions


Ulipristal acetate is a selective progesterone receptor modulator (SPRM) with tissue-selective partial antagonist activity. It has clinical use both as an emergency contraceptive and as a treatment for uterine fibroids. Ulipristal acetate acts as a partial antagonist on the hypothalamic–pituitary–ovarian axis to inhibit or delay ovulation without affecting human embryo implantation. As a progesterone antagonist, Ulipristal acetate selectively suppresses neo-vascularization, cell proliferation, and survival in uterine fibroid cells, but not in normal myometrial cells.


Ulipristal acetate is known to reduce uncontrolled bleeding due to post uterine fibroid surgery.


Packaging


10, 50 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyOOLLAFOLCSJHRE-ZHAKMVSLSA-N
InChI1S/C30H37NO4/c1-18(32)30(35-19(2)33)15-14-27-25-12-8-21-16-23(34)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)31(4)5/h6-7,9-10,16,25-27H,8,11-15,17H2,1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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