TWS119

TWS119

Stock Code: 3574689
Manufacturer Part No: SML1271-5MG
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Application


TWS119 has been used as glycogen synthase kinase-3? (GSK-3?) GSK3? inhibitor.


Biochem/physiol Actions


TWS119 favors the ??T cells survival and proliferation by activating the mammalian target of rapamycin (mTOR) pathway. It also promotes the expression of T-cell factor 1 (TCF1) and modulates cytokine production.


TWS119 is a potent Glycogen synthase kinase-3β (GSK-3β) inhibitor that can induce neurogenesis in embryonic stem cells (ESCs).


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyVPVLEBIVXZSOMQ-UHFFFAOYSA-N
InChI1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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