Tiagabine hydrochloride, >=98% (HPLC)

Tiagabine hydrochloride, >=98% (HPLC)

Stock Code: 3573993
Manufacturer Part No: SML0035-10MG
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Application


Tiagabine hydrochloride was used to study serotoninergic transmission in G1 cells. It has also been used to study its anti-aging effects on the sensory neurons of C. elegans.


Biochem/physiol Actions


Tiagabine increases the synaptic GABA and enhances the neuronal inhibition. It is effective as adjunctive treatment of epilepsy and anxiety disorders.


Tiagabine hydrochloride is an anticonvulsant and selective GABA reuptake inhibitor through inhibition of the synaptic GABA transporter GAT1.


Features and Benefits


This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


This compound was developed by Cephalon. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


This compound is featured on the GABA Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


10, 50 mg in glass bottle

Colourwhite to beige
InChI keyYUKARLAABCGMCN-PKLMIRHRSA-N
InChI1S/C20H25NO2S2.ClH/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23;/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23);1H/t16-;/m1./s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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