TERIFLUNOMIDE
Application
Teriflunomide has been used as a dihydroorotate dehydrogenase (DHODH) inhibitor.
Biochem/physiol Actions
Teriflunomide is an orally available anti-inflammatory immunomodulator. It blocks the activity of dihydroorotate dehydrogenase, preventing pyrimidine synthesis and T and B cell proliferation and function. Teriflunomide has been used to treat rheumatoid arthritis and was recently approved for multiple sclerosis.
Packaging
10, 50 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | −20°C |
| Solubility | DMSO: 5 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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