SR-18292 MALEATE
Application
SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor ? coactivator 1 ? (PGC1?) inhibitor to study the protective effects of pioglitazone on demyelinated axons.
Biochem/physiol Actions
SR-18292 is a potent and specific inhibitor of hepatic gluconeogenesis via increased acetylation of PGC-1α and suppression of gluconeogenic gene expression. SR-18292 reduces blood glucose and increases hepatic insulin sensitivity in mouse models of T2D.
| Colour | white to beige |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | DMSO: 2 mg/mL, clear |
| Form | powder |
| Assay | ≥98% (HPLC) |
There are no downloads for this product.
