SR-18292 MALEATE

SR-18292 MALEATE

Stock Code: 3575872
Manufacturer Part No: SML2146-25MG
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£515.36 (exc VAT) per 25MG
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Application


SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor ? coactivator 1 ? (PGC1?) inhibitor to study the protective effects of pioglitazone on demyelinated axons.


Biochem/physiol Actions


SR-18292 is a potent and specific inhibitor of hepatic gluconeogenesis via increased acetylation of PGC-1α and suppression of gluconeogenic gene expression. SR-18292 reduces blood glucose and increases hepatic insulin sensitivity in mouse models of T2D.

Colourwhite to beige
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 2 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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