Biochem/physiol Actions
SK-216 is an orally active potent and selective inhibitor of Plasminogen activator inhibitor-1 (PAI-1) that inhibits tumor progression and angiogenesis. SK-216 inhibits migration and tube formation of cultured human umbilical vein endothelial cells induced by various angiogenic factors. SK-116 prevents a formation of gastro-intestinal polyps in Min mice.
| Colour | white to beige |
|---|---|
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | room temp |
| Solubility | H2O: 0.5 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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