SB 699551 DIHYDROCHLORIDE

SB 699551 DIHYDROCHLORIDE

Stock Code: 3574170
Manufacturer Part No: SML0853-5MG
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£133.30 (exc VAT) per 5MG
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Application


SB 699551 dihydrochloride has been used to identify the antagonism of 5-HT2AR in cell culture-derived hepatitis C virus (HCVcc).


Biochem/physiol Actions


SB 699551 dihydrochloride is also known as (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4?-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride). It is considered as a useful tool to explain the physiological roles of the 5-ht5A receptor.


SB-699551 is a 5-HT5A receptor antagonist, (pKi = 8.3) with 100-fold selectivity over other 5-HT receptor populations. SB-699551 completely blocks 5-HT-induced [35S]GTPγS membrane binding in cells expressing recombinant guinea pig 5-HT-5A.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityH2O: 1 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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