SB 204741, , >98% (HPLC)

SB 204741, , >98% (HPLC)

Stock Code: 3573888
Manufacturer Part No: S0693-10MG
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Application


SB 204741 has been used as a 5-hydroxytryptamine receptor 2B (Htr2B) antagonist: to inhibit Htr2b signaling to test its effect on hepatic stellate cell (HSC) activation in three-month-old adult zebrafishto test its effect on the inhibition of fluoxetine effects in depressive-like behavioral studies in miceto test its effect in reducing scratching behavior evoked by sertraline in mice


Biochem/physiol Actions


5-HT2B serotonin receptor antagonist.


SB 204741 reduces the synaptic facilitation induced by the low dose of buprenorphine in spinal C-fiber synapses.


Features and Benefits


This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


Legal Information


Sold for research purposes under agreement from GlaxoSmithKline


Packaging


10, 50 mg in glass bottle

Colouroff-white to tan
Quality Level100
InChI keyUSFUFHFQWXDVMH-UHFFFAOYSA-N
InChI1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19)
ManufacturerSIGMA-ALDRICH
Formsolid
Assay>98% (HPLC)

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