Safinamide mesylate salt, >=98% (HPLC)

Safinamide mesylate salt, >=98% (HPLC)

Stock Code: 3573985
Manufacturer Part No: SML0025-25MG
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£596.14 (exc VAT) per 25MG
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Application


Safinamide mesylate salt may be used in cell signaling studies.


Safinamide mesylate salt has been used as a reference drug to study its inhibitory effect on human monoamine oxidases (hMAO-A and hMAO-B).


Biochem/physiol Actions


Safinamide mesylate prevents dopamine reuptake and is effective in the treatment of epilepsy and Parkinson′s disease.


Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, safinamide is voltage-dependent sodium and calcium channel blocker. It appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.


Features and Benefits


This compound is featured on the Calcium Channels and Dopamine and Norepinephrine Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


5, 25 mg in glass bottle

Colourwhite to tan
Quality Level100
InChI keyYKOCHIUQOBQIAC-YDALLXLXSA-N
InChI1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-5-7-16(8-6-13)22-11-14-3-2-4-15(18)9-14;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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