RP-?8-?BR-?CGMPS SODIUM SALT

RP-?8-?BR-?CGMPS SODIUM SALT

Stock Code: 3575160
Manufacturer Part No: SML1614-5MG
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Biochem/physiol Actions


Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition.

Colourwhite to beige
Quality Level100
InChI keyCHTSSROWUAICIL-GMKUFTCMSA-M
InChI1S/C10H11BrN5O6PS.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(21-8)1-20-23(19,24)22-5;/h2,4-5,8,17H,1H2,(H,19,24)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formlyophilized solid
Assay≥98% (HPLC)

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