ROSTAFUROXIN

ROSTAFUROXIN

Stock Code: 3574516
Manufacturer Part No: SML1139-25MG
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£516.75 (exc VAT) per 25MG
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Biochem/physiol Actions


Rostafuroxin is a digitoxygenin derivative that selectively antagonizes the effects of endogenous ouabain on the Na+,K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes. Rostafuroxin lowers blood pressure (BP) in animal models of hypertension.


Rostafuroxin is a derivative of digitoxigenin. It protects animal models against podocyte lesions and proteinuria by counteracting mutant ?-adducin and ouabain-mediated effects.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyAEAPORIZZWBIEX-DTBDINHYSA-N
InChI1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,1
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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