Biochem/physiol Actions
RO8191 is an orally available, potent and specific type I interferon receptor agonist that directly binds to IFN-α receptor 2 (IFNAR2). RO8191 suppresses HCV replication without inducing host cell toxicity.
RO8191 is an imidazonaphthyridinecompound, which activates interferon(IFN) signals, IFN-stimulated genes (ISGs) expression and Janus kinase (JAK)/signal transducers and activators of transcription (STAT) phosphorylation.
Packaging
5, 25 mg in glass bottle
| Colour | white to beige |
|---|---|
| Quality Level | 100 |
| Manufacturer | SIGMA-ALDRICH |
| Storage Temp. | 2-8°C |
| Solubility | DMSO: 0.5 mg/mL, clear (warmed) |
| Form | powder |
| Assay | ≥98% (HPLC) |
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