RHYNCHOPHYLLINE

Stock Code: 3576176
Manufacturer Part No: SML2345-5MG
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Biochem/physiol Actions


Rhynchophylline is a spirocyclic alkaloid isolated from Uncaria species that exibits numerous pharmacological activities including hypotensive, neuroprotective, anticonvulsive, antiepileptic, antiarrhythmic, anticoagulant, antispasmodic, and sedative. Rhynchophylline modulates voltage-gated K+ (Kv) channel slow inactivation in mouse neuroblastoma N2A cells. Also it acts as noncompetitive antagonists of NMDA receptor channels in Xenopus oocytes.

Colourwhite to beige
InChI keyDAXYUDFNWXHGBE-KAXDATADSA-N
InChI1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-,
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 2 mg/mL, clear (warmed)
Formpowder
Assay≥95% (HPLC)

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