Propyl gallate, antioxidant, >=98.0% (HPLC)

Propyl gallate, antioxidant, >=98.0% (HPLC)

Stock Code: 3573225
Manufacturer Part No: 48710-100G-F
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£101.96 (exc VAT) per 100G
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Application


Used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.


Biochem/physiol Actions


An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 µM when it was combined with copper concentrations at 5 µM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.


An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis.


Reconstitution


Prepare a 0.1M solution in glycerol:PBS (9:1)

Quality Level200
mp146-149 °C, 146-149 °C (lit.)
InChI keyZTHYODDOHIVTJV-UHFFFAOYSA-N
InChI1S/C10H12O5/c1-2-3-15-10(14)6-4-7(11)9(13)8(12)5-6/h4-5,11-13H,2-3H2,1H3
ManufacturerSIGMA-ALDRICH
Formsolid
Assay≥98.0% (HPLC)

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