Procarbazine hydrochloride, >=98% (HPLC)

Procarbazine hydrochloride, >=98% (HPLC)

Stock Code: 3573995
Manufacturer Part No: SML0036-10MG
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£146.25 (exc VAT) per 10MG
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Application


Procarbazine, an antineoplastic alkylating agent, may be used to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an anticancer agent. It may be used to study new combination of anticancer drugs.


Procarbazine hydrochloride has been used to study its physicochemical property.


Biochem/physiol Actions


Procarbazine is an antineoplastic alkylating agent widely used in cancer chemotherapy in combination with other compounds. It has multiple mechanisms of action. Procarbazine inhibits protein, RNA and DNA synthesis in addition to being an alkylating agent.


Procarbazine is metabolized to azoprocarbazine either by cytochrome P450 enzyme and monoamine oxidase in an NADPH (nicotinamide adenine diphosphate) dependent or independent manner. It is considered neurotoxic. Procarbazine is used in combination with therapy for treating Hodgkin?s disease.


Packaging


10, 50 mg in glass bottle

Colourwhite to tan
Quality Level100
InChI keyDERJYEZSLHIUKF-UHFFFAOYSA-N
InChI1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: ≥18 mg/mL
Formpowder
Assay≥98% (HPLC)

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