PKUMDL-WQ-2201

PKUMDL-WQ-2201

Stock Code: 3575631
Manufacturer Part No: SML1965-5MG
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£113.52 (exc VAT) per 5MG
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Biochem/physiol Actions


PKUMDL-WQ-2201 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells. PKUMDL-WQ-2201 binds to allosteric site II, which is located in the substrate-binding domain. PKUMDL-WQ-2201 inhibits tumor growth of MDA-MB-468 xenografts in mice.

Colourwhite to brown
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 15 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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